Pharmaceutical intermediates

ACYCLOVIR :
2-oxa-1,4-butanedil diacetate

ADENOSINE :
6-chloropurine

ALLOPURINOL :
3-mopholine-2-cyanocrylamide
5-amino-4-pyrazole carboxamide hemisalfate
ethoxymethylene cyanoacetic acid ethyl ester

AMBROXOL :
trans-4-amino cyclohexyphenol
2-amino-3,5-dibromo benzaldehyde

AMILORIDE :
3-amino-5,6-dichloropyrazine2-methyl formate
3,5-diamino-6-chloropyrazine-2-methyl formate

AMIODARONE :
2-butyl-3-(p-hydroxybenzoyl)benzofuran
2-butyl-3-(3',5,5-diido-4-hydroxybenzoyl) benzofuran

ATENOLOL :
4-aminophenyl acetic acid
4-hydroxyphenyl acetamide

ATORVASTATIN :
(r)-4-cyano-3-hydroxybutyric acid ethyl ester
(4r-cis)-1,1-dimethylethyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
(4r-cis)-1,1-dimethylethyl-6-aminoethyl-2,2-dimethyl-1,3-dioxane-4-acetate
4-fluoro-alpha-[2-methyl-1-oxopropyl]-gama-oxo-n,beta-diphenylbenzene butaneamide
(4r-cis)-1,1-dimethylethyl-6-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate

AZATHIOPRINUM :
5-chloro-1-methyl imidazole
5-chloro-1-methyl-4-nitroimidazole

BAMBUTEROL :
3,5-dihydroxy benzoic acid
3,5-dihydroxy acetophenone
3,5-diphenoxy acetophenone

BENAZEPRIL :
4-hydroxyphenethylamine
tert-butyl-(s)-(3-amino-2-oxo-2,3,4,5-tetrahydro benzo[b]azepin-1-yl)acetate

BRODIMOPRIM :
4-bromo-3,5-dihydroxybenzoic acid
4-bromo-3,5-dimethoxybenzoic acid
4-bromo-3,5-dimethoxy benzoyl chloride
4-bromo-3,5-dimethylbenzaldehyde

BROMHEXINE :
2-amino-3,5-dibromotoluene
2-diacetylamino-3,5-dibromobenzyl bromide
n-methyl-n-cyclohexyl-2-amino-3,5-dibromophenylmethylamine

BUFLOMEDIL :
1,3,5-trimethoxybenzene
4-chlorobutyryl chloride
1-(4-chlorobutyryl)-2,4,6-trimethoxybenzene

BUMETANIDE:
4-chloro-3,5-dinitrobenzoic acid
4-phenoxy-3,5-dinitrobenzoic acid
5-nitro-4-phenoxy-3-aminosulfonyl benzoic acid
5-amino-4-phenoxy-3-aminosulfonyl benzoic acid

BUTENAFINE :
4-(tert-butyl)benzyl chloride
4-(tert-butyl)benzyl bromide
n-methyl-1-naphthalenemethylamine hcl

CANDESARTAN :
2-cyano-4'-bromomethylbiphenyl

CAPTOPRIL :
d-3-acetylthio-2-methyl propionyl-l-proline

CARBAMAZEPINE :
iminodibenzyl
chlorocabonyl liminostilben

CARVEDIOL :
4-hydroxycarbazole
1,2,3,4-terahydro-4-oxocarbazole
2-(2-methoxyphenoxy)ethylamine hcl


CEFOTAXIME:
s-(2-benzothiazoleyl)-2-(2-aminothiazol-4-yl)-(z)-2-methoxyimino thioacetate
2-methoxyimino-2-(2-aminothiazole-4-yl)-acetic acid anhydrous

CEFOTIAM :
d-(-)-a-(4-ethyl-2,3-dioxo piperzinyl) carboxyamide-4-hydroxyphenyl acetic acid
2-amino-4-thiazolyl-acetic acid

CELECOXIB :
1-(4-methylphenyl)-4,4,4-trifluorobutane-1,3-dione
4-sulfamoylphenyl hydrazine hcl

CHLORPROTHIXENE :
2-chloro-9h-ph-thioxanthen-9-one-(2-chlorothioxathone)
2-chloro-9-(3-dimethylaminopropyl)-ph-thioxanthe-9-ol

CHLORTHALIDONE :
2-(3-amino-4-chlorobenzoyl) benzoic acid

CLOFIBRATE :
clofibric acid

CLONAZEPAM :
2-amino-5-nitro-2'-chlorobenzophenone

CLOPIDOGREL :
2-thiophene ethanol
2-thiophene ethylamine
r,s-2-chloro-(alpha bromo)phenylacetic acid
(dl)-methyl-alpha-(2-thienylethamino)(2-chlorophenyl)acetate hcl

CLOZAPINE
8-chloro 11 oxy-10-11,dihydro-5H-dibenzo-1,4-diazepine

CYCLOPHOSPHAMIDE :
bis-(chloroethyl)amine hcl

CYPROTERONE ACETATE :
1,6-didehydro-17a-hydroxy progesterone
1,6-didehydro-17a-acetoxy progesterone
1,2-a-methylene-6-didehydro-17a-acetoxy progesterone
1-chloromethyl-6-chloro-6-dehydro-17a-acetoxy progesterone

DACARBAZINE :
4-formamido-5-aminoimidazole hcl
5-aminoimidazole-4-foramido hcl

2-DEOXY CYTINE
cytosine   

DICLAZURIL :
2,6-dichloro-alpha-(4-chlorophenyl)-4-nitrophenzyl cyanide
4-amino-2,6-dichloro-alpha-(4-chlorophenyl)phenzyl cyanide

DICLOFENZC
Indolinone

DILTIAZEM
Para anisaldehyde
Ortho amino thiophenol
Methyl-2-chloro acetate
N,N-Dimethyl amino ethyl chloride

DOMPERIDONE :
1-benzyl-3-methoxycarbonyl-4-piperidone
2-b-(chloropropyl)-1,3-dihydro-2h-benzimidzole-2-one
1-(4-piperidinyl)-1,3-dihydroxy-2h-5-chloro benzimidazolone

DOXAZOSIN :
2-amino-4,5-dimethoxybenzoic acid
2-chloro-4-amino-6,7-dimethoxyquinazoline

DOXEPIN :
phthalide
11-dihydrodibenz[b,c]oxcpin-11-one
11-(3-dimethylaminopropyl-6,11-dihydrodibenz[b,c]oxcpin-11-ol

ETODOLIC
2-ethyl phenyl hydrazine hcl
methyl propionyl acetate
2,3-dihydro furan

ENALAPRIL :
n-[1-(s)-ethoxycarbonyl-3-phenylpropyl]-l-alanine

ESMOLOL :
3-[4-[2-hydroxy-3-[(1-methylethyl)amino] propoxy]phenyl]acrylate hcl

FAMCICLOVIR :
2-amino-6-hydroxypurine
6-chloropurine
2,6-dichloropurine
2-amino-6-chloropurine
9-(4-acetoxy-3-acetoxymethylbut-1-yl)-2-amino-6-chloropurine

FELODIPINE :
2,3-dichlorobenzaldehyde

FENOFIBRATE :
4-chloro-4'-hydroxybenzophenone
2-[4-(p-chlorobenzoyl) phenoxy]-2'-methyl-propionue acid

FINASTERIDE :
androst-3-one-4-ene-17b-carboxylic acid
androst-4-aza-3-one-17b-butyl carboxamide
3-oxo-4-aza-5a-androstane-17b-carboxylic acid

FIPRONIL :
2,6-dichloro-4-trifluoromethyl aniline

FLECAINIDE :
2,5-bis-(2,2,2-trifluoroethoxy)benzoic acid

FLUCONAZOLE :
2-chloro-2',4'-difuloro acetophenone
2,4-difluoro-a-(1h-1,2,4-triazol-1yl) acetophenone

FLUNARIZINE :
n-mono-[4,4'-fluorobenzyl] methyl piperazine

FLUOROURACIL :
L2-mercapto-4-hydroxy-5-fluoropyrimidine

FLUOXETINE :
3-methylamino-1-phenyl-propanol
3-hydroxy-n-methyl-3-phenyl propylamine

FLUORO URACIL
Methyl fluoro acetate
Ethyl fluoro acetate

FLURAEPAM :
2-amino-5-chloro-2'-fluorobenzophenone

FLURAZOPAN :
2-amino-5-chloro-2'-fluorobenzophenone
7-chloro-5-(2-fluorophenyl)1,3-dihydro-1,4-benzodiazepine-2-one

FLUROBENDAZOLE :
4-chloro-4'-fluoro-3-nitrobenzophenone

FLUTAMIDE :
3-trifluoromethyl-4-nitro aniline

FORMOTEROL :
3-nitro-4-hydroxyacetophenone

FUROSEMIDE :
2,4-dichloro-5-sulfamide benzoic acid
2,4-dichloro-5-aminosulfomylbenzoic acid
2-amino-4-chloro-5-aminosulfomyl benzoic acid

GABAPENTINE :
1,1-cyclohexane diacetic acid monoamide

GATIFLOXACINE :
3-hydroxy-2,4,5-trifluorbenzoic acid
3-methoxy-2,4,5-trifluorobenoic acid
alpha-(3-methoxy-2,4,5-trifluorobenzoyl)-beta-cyclopropylamine-carylic acid ethyl ester
1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinoline carboxylic acid ethyl ester
1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinoline carboxylic acid

GEMFIBROZIL :
2,5-dimethyl phenol
isobutyl-5-chloro-2,2-dimethylvalerate

GLIBENCAMIDE :
5-chloro-2-methoxy
4-(2-aminoethyl)benzene sulfonamide
4-[2-(5-chloro-2-methoxybenzamide)ethyl]benzene sulfonamide

GLICLAZIDE :
n-amino-3-azabciclo(3,3,0) octane hcl
Amino heterocyclicring
p-toluene sulfonyl urea

GLIMEPIRIDE :
3-ethyl-4-methyl-2-oxo-pyrroline
trans-4-methyl cyclohexylamine

GLIQUIDONE :
4,4-dimethyl-7-methoxyisochroman-1,3-dione
n-[2-(4-sulfonamidylphenyl)ethyl]-4,4-dimethyl-7-methoxy-1,2,3,4-tetrahydroisoquinoline-1,3-dione
GRANISETRON :
1-methyl-1h-indazole-3-carboxychloride

HALOPERIDOL :
4-(4-chlorophenyl)-4-hydoxypiperidine

IMIQUIMOD :
3-amino-2-chloro-4-[(2-methylpropyl)amino]quinoline
IRBESARTAN :
2-cyano-4'-bromomethylbiphenyl
2-butyl-1,3-diazapiro[4,4]non-1-en-4-one hcl
2-(1h-1-triphenyl-tetrazol-5-yl)-4'-bromomethyl diphenylene
1-amino-1-cyclopentane carboxamide

IRINOTECAN :
campthotecin
7-ethylcampthotecin
7-ethyl-10hydroxycampthotecin

ITRACONAZOLE
cis-[2-(2,4-dichlorophenyl)-2-(1h-1,2,4-triazole-1-ylmethyl)-1,3-dioxolan-4-yl]-methyl methanesulfonate
2,4-dihydro-4-[[4-(4-hydroxyphenyl)-1-piperazinyl]-phenyl]-2-(1-methylpropyl)- -3h-1,2,4-triazole-3-one

KETOCOANZOLE
Activityester -1
cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-yl-methyl)-1, 3-dioxolane-4-yl]methanol,methyl sulfonate
ActiveEster-2
cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-yl-methyl)-1, 3-dioxolane-4-yl]methanol-p-methylbenzenesulfonate
Cis-Bromo-ester:
(2rs,4rs)-2-(bromomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4-methanol benzoate(ester)
Branched chain:1-acetyl-4-(4-hydroxyl phenyl) piperazine

LANSOPRAZOLE :2,2,2-trifluoroethanol
2-hydroxymethyl-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine
2-chloromethyl-3-methyl-4-(2,2,2-trifluoroethoxy)pyridine

LEFLUNOMIDE :
5-methylisooxazole-4-benzoic acid

LEVOFLOXACIN :
s-(+)-2-amino propanol

LINEZOLID :
3,4-difluoro nitro benzene

LISINOPRIL :
ethoxy carbonyl phenyl propyl-n-trifluoro acetyl-l-lysine

LOPERAMIDE :
4-chlorophenyl-4-hydroxy piperidine
3,3-diphenyl-2-furlidine amino bromide

LORATDINE :
2-cyano-3-methylpyridine
n-methyl-4-chloro-piperdine hcl
5-amino-4,6-dichloro-2-methyl pyrimidine
3-[2-(3-chlorophenyl)ethyl]-2-pyridine carbonitrile
3-[2-(3-chlorophenyl)ethyl]-2-pyridine carboxchloride
8-chloro-6,11-dihydro-5h-benzo-(5,6)cyclohepta(1,2-pyridine-11-one)

LOSARTAN :
2-cyano-4'-methylbiphenyl
2-cyano-4'-bromomethylbiphenyl

MELOXICAM :
2-amino-5-methylthiazole
2-methyl-4-hydroxy-2h-1,2-benzothiazine-3-carboxylic acid ethyl ester-1,1-dioxide

METHYLDOPA :
3-hydroxy-4-methoxybenzaldehyde
3,4-methylenedioxyphenyl-2-propanone

METOPROLOL :
4-(2-methoxyethyl)phenol

MIDAZOLAM :
2-amino-5-chloro-2'-fluorobenzophenone
2-aminomethyl-7-chloro-2,3-dihydro-5-(2-fluorophenyl)-1h-1,4-benzodiazepine dimaleate
7-chloro-1,3-dihydro-5-(2-fluorophenyl)-2-nitromethylene-2h-1,4-benzodiazepine
8-chloro-3a,4-dihydro-6-(2-fluorophenyl)-1-methyl-3h-imidaz[1,5a][1,4]benzodiazepine

MODAFINIL :
diphenylmethanol
diphenylmethyl thioacetic acid
ethyl diphenylmethyl thioacetate

MOXIFLOXACIN :
2,3-pyridinedicarboxylic anhydride

MOXONIDINE :
5-amino-4,6-dichloro-2-methylpyrimidine

NAPROXEN
Trimethyl ortho formate
Propionyl chloride
2-naphthol
yara yara
n-octyl glucamine
DL-Naproxen

NATEGLINIDE :
trans-4-(1-methylethyl)cyclohexane carboxylic acid

NEBIVOLO :
5-fluoro-2-hydroxy acetophenone

NELFINAVIR :
3-acetoxy-2-methylbenzoic acid

NIZATIDINE :
dimethyl aminoacetonitrile
dimethyl aminothio acetmide
2-dimethylaminomethyl-4-chloromethyl-4-hydroxyl thiazoline
2-dimethylaminomethyl-4-chloromethylthiazole hcl
2-(n,n-dimethylaminomethyl)-4-carbethoxy thiazole
s-(2-dimethylaminomethyl)-4-thiazolemethyl isothioure dihcl
2-(dimethylaminomethyl)4-thiazolemethanol
n-(2-thioethyl)-n'-methyl-2-nitro-1',1-ethendiamine
n-(2-chloroethyl)-n'-methyl-2-nitro-1',1-ethendiamine

OMEPRAZOLE :
2,3,5-Trimethyl pyridine
2-mercapto-5-methyl 1H benzimidazole
2-chloromethyl-3,5-dimethyl-4-methoxypyridine HCL
4-methoxy-3,5-dimethyl-2-hydroxymethyl pyridine

ONDANSETRONE :
1,2,3,9-trtrahydro-9-methyl-4h-carbazol-4-one
3-[(dimethylamino)methyl]-1,2,3,9-tetrahydro-9-methyl-4h-carbazole-4-one

OXYBUTYNIN :
cyclohexylmandelic acid methyl ester

PANTOPRAZOLE :
2-chloromethyl-3,4-dimethoxy pyridine hcl
3-methoxy-2-methyl-4-(1h)-pyridone
4-chloro-3-methoxy-2-methyl pyridine-n-oxide
5-difluormethoxy-2-mercapto-1h-benzimidazole

PAROXETINE :
trans-4-(4-fluorophenyl)-3-hydroxymethyl piperidine
4r-(4'-fluorophenyl)-3s-[(3',4'-methylenedioxyphenoxyl)methyl]-n-methylpiperidine

PENCICLOVIR :
2-amino-6-chloropurine

PERPHENAZINE :
n-(2-hydroxyethyl) piperazine
PIROXICAM:
2-methyl-4-hydroxy-2h-1,2-benzothiazine-3-carboxylic acid ethyl ester-1,1-dioxide

PRAZOSIN :
6,7-dimethoxy quinazoline-2,4-dione 98% min.
6,7-dimethoxy - 2 - chloro 4-amino quinazoline 98% min.
1(2-furoyl) piperazine 98% min.
4-amino-2-chloro-6,7-dimethoxyquinazoline

QUETIAPINE :
2-(2-chloroethoxy)ethanol
dibenzo[b,f][1,4]thiazepine-11(oh)-one

RALOXIFENE :
4-(2-piperidinoethoxy)benzoic acid hcl
6-methoxy-2-(4-methoxyphenyl)benzothiophene

RANITIDINE :
1-methoxy-1-methylamino-2-nitroethylene

RIFAMPICIN :
1-amino-4-methylpiperazine

RIMANTADINE :
1-bromo adamantane
1-adamantyl methyl ketone
1- adamantane carboxulic acid

ROSIGLITAZONE
2,4-Thiazolidine Dione
SERTRALINE :
4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-naphthalone
4-(3,4-dichlorophenyl)-1-tetralone

RISEDRONATE
Acetyl Pyridine

SIBUTRAMINE :
1-(4-chlorophenyl)cyclobutanecarbonitril

SILDENAFIL :
1-Methyl-3-Propyl-4-Nitro-5-Carboxamide Pyrazole
4-amino-1-methyl-3-n-propylpyrazole-5-carboxamide
5-(2-ethoxyphenyl)-1methyl-3-propyl-6,7-dihydro-1h-pyrazolo pyrimidin-7-one

SODIUM DANTROLENE
5-(P-Nitrophenyl)-2-furaldehyde

SOTALOL :
4-(chloroacetyl)phenylmethane sulfonamide
4-(isopropylamino)phenylmethane sulfonamide

STARVUDINE :
3',5-dimethane sulfonyl thymidine
2-dexoy-3,5-epoxythymine

SULPIRIDE :
1-ethyl-2-aminmethylene pyrrolidine
2-methoxy-5-sulfamoyl benzoic acid

SUMATRIPAN:
4-hydrazino-n-methyl-benzene methane sulfonamide hcl
4(dimethyl amino)butyraldehyde dimethyl acetal

T.M.P :
4,5-trimethoxy-2-methoxymethyl cynnamonitrile
TAZOBACTAM :
enzhydryl-6,6-dibromopenicillanate-1-oxide

TEGASEROD :
5-methoxy-3-indole carboxaldehyde

TELMISARTAN :
2-cyano-4'-bromomethylbiphenyl

TERFENADINE
3,5-diethoxy acetopheone

TERAZOSINE :
4-amino-2-chloro-6,7-dimethxoyquinazoline
2-amino-4,5-dimethoxybenzoic acid

TERBINAFINE :
3,3'-dimethyl-1-butynene
trans-1,3-dichloropropylene
methyl naphthalene-1-yl-methylamine

THIOCTIC ACID :6,8- dichloro ethyl caprylate

THIORIDAZINE :
2-thomethyl phenothiaize
bata-ethylchloride-n-methyl piperidine hcl

TIAPRIDE :
2-methoxy-5-methylsulfonyl benzoic acid

TIBOLONE :
7a-methyl-3,3-dimethoxy-5(10)-estrene-17-one

TIMOLOL :
3,4-dichloro-1,2,5-thiadiazole
3-morpholine-4-chloro-1,2,5-thiadiazole
s-(-)-tert-butylamine-1,2-propylene glycol

TOPOTECAN :
iodobenzene
camptothecinum
10-hydroxycamptothecinum

TORASEMIDE :
4-[(3-methylphenyl)amino]-3-pyridinesulfonamide

TORSEMIDE :
4-(3-methylphenyl)aminopyridine-3-sulfonamide

TOSUFLOXACIN :
ethyl-(2,6-dichloro-5-fluoronicotinoyl)acetate

TRAMADOL
Meta bromo anisole

TRAPIDIL :
3-amino-1h-1,2,4-triazole

TRIAMTERENE :
2,4,6-triaminopyrimidine
2,4,6-triamino-5-nitropyrimidine

TRIAZOLAM :
2-amino-5-chloro-2'-chloro benzopheone

TRIMEBUTINE :
3,4,5-trimethoxy benzoic acid

TROVAFLOXACIN :
3-hydroxy acetophenone
3-amino acetophenone

VALACICLOVIR :
2-amino-6-chloropurine

VALSARTAN :
2-(1h-1-triphenyl-tetrazol-5-yl)-4'-bromomethyl diphenylene

VENAFAXINE :
1-[cyano-(4-methoxyphenyl)]cyclohexanol
1-[2-amino-1-(4-methoxyphenyl)ethyl]cyclohexanol
n,n-dimethyl-2-(1-hydroxy cyclohexyl)-2-(4-methoxy) acetamide

VITAMIN D2 :
3,5-dinitrobenzoic acid
3,5-dinitrobenzoyl chloride

VITAMIN H :
cis-1,3-dibenzylimidazole-2-one-4,5-dicarboxylic acid

WARFARIN :
4-hydroxycoumarin

ZALEPLON :
3-amino-1h-pyrazole-4-carbonitrile

ZOLPIDEM :
2-(4-methylphenyl)-6-methylimidazole pyridine
2-(4-methylphenyl)-6-methylimidazole pyridine-3-acetonitrile

ZOPICLONE :
2,3-pyrazine dicarboxylic anhydride
2-amino-5-chloropyridine
6-(5-chloro-2-piperidinyl)-6,7-dihydro-7-hydroxy-5h-pyrrolo[3,4-b]pyrazine-5-one